Phoenixville Day Care Center was first established in 1965 as a volunteer program to provide afternoon care to children who came home from school to an empty house. It was the brainchild of Dr. Lola Reed, a well-known pediatrician. In 1966, Phoenixville Day Care Association was charted as a non-profit 501 (c) 3 organization and a day care program began with the purchase of the Bishop Funeral Home on 310 Main Street. Misty Webb became the first Executive Director in 1966. She developed a successful program that provided for the physical and emotional needs of the children from low-income families in Phoenixville. Later on a curriculum was written and degreed experienced staff members were hired to better meet the needs of the children and an infant and toddler program was included. The name was changed to Phoenixville Area Children's Learning Center to emphasize the inclusion of a pre-school education.
In September, 2008 a new facility was opened at the Franklin Commons Campus. With the opening of this center PACLC is able to accomodate more children.